Survivin Polyclonal Antibody(C-terminal )
簡(jiǎn)要描述:Survivin Polyclonal Antibody(C-terminal )宿主: Polyclonal, Rabbit,IgG反應(yīng)性: Human;Mouse;Rat應(yīng)用: WB;IHC;IF;ELISA
產(chǎn)品型號(hào): YP-Ab-00526
所屬分類(lèi):多克隆抗體
更新時(shí)間:2024-11-01
詳細(xì)說(shuō)明:
Survivin Polyclonal Antibody(C-terminal )
抗體,也叫免疫球蛋白(Ig),是一種能特異性結(jié)合抗原的糖蛋白,而抗原是在易感染動(dòng)物體內(nèi)引發(fā)抗體產(chǎn)生的物質(zhì)。在體內(nèi),抗體是由于外源性分子的侵襲而產(chǎn)生的??贵w以一個(gè)或者多個(gè)Y字形單體存在,每個(gè)Y字形單體由4條多肽鏈組成,包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈?zhǔn)歉鶕?jù)它們的分子量大小來(lái)命名的。Y字形結(jié)構(gòu)的頂端是可變區(qū),為抗原結(jié)合部位。任何一個(gè)抗體的輕鏈都可以分為κ或λ型(基于小分子多肽結(jié)構(gòu)上的差異),每一個(gè)抗體的重鏈則決定了它的類(lèi)或型。
產(chǎn)品詳情
Survivin Polyclonal Antibody detects endogenous levels of Survivin protein.
免疫原詳細(xì)信息
The antiserum was produced against synthesized peptide derived from human Survivin. AA range:86-135
相關(guān)試劑
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
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